Immunologic and Hematological Abnormalities in Necrotizing Enterocolitis

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Immunologic and Hematological Abnormalities in Necrotizing Enterocolitis.

Necrotizing enterocolitis (NEC) is a leading cause of mortality in preterm infants. This article reviews the immunologic and hematological abnormalities typically seen in infants with NEC, such as elevated plasma cytokine levels, thrombocytopenia, increased or decreased neutrophil counts, low monocyte counts, and anemia. Some of these findings may provide important diagnostic and prognostic inf...

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Haematological abnormalities in neonatal necrotizing enterocolitis.

OBJECTIVE Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in preterm infants born prior to 32 weeks gestation or with a birth weight less than 1500 grams. In this article, we review hematological abnormalities associated with NEC. METHODS A literature search was performed using the databases PubMed, EMBASE, and Scopus, and the electronic archive of abstracts pres...

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Necrotizing enterocolitis report of 20 cases

Necrotizing enterocolitis is a disease of unknown origin. Epidemiological observations emphasize the potential roles of  infection, enteric feeding and local vascular compromise of the Gastrointestinal tract in the pathogenesis of this disease. Clinical findings include signs of sepsis , plus abdominal distention , vomiting, bloody stool and occasionally , signs of intestinal perforation and pe...

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Necrotizing enterocolitis

During the 3 years 1972-74, 17 infants were treated for necrotizing enterocolitis (NEC) in the Neonatal Unit at University College Hospital. The incidence of the illness was 0 2% of live births in the hospital and 2.7% of those referred from elsewhere. The mean birthweight of the affected infants was 1832 g (range 878-3850 g) and mean gestational age 33 weeks (range 28-40 weeks). The illness wa...

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Necrotizing enterocolitis.

Necrotizing enterocolitis (NEC) is an important cause of neonatal morbidity and mortality. During the last few years, there was an increase in the incidence of this disease, associated with a better knowledge of NEC, and an increase in survival rate, associated with the development, even from a technological point of view, of neonatal intensive care units. In this study, the authors first perfo...

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ژورنال

عنوان ژورنال: Clinics in Perinatology

سال: 2015

ISSN: 0095-5108

DOI: 10.1016/j.clp.2015.04.014